Neurons communicate with other neurons (and muscles) with tiny chemicals made and packaged in the body called neurotransmitters. Because neurons do not actually touch other neurons, neurotransmitters 'carry' the message from the Presynaptic neuron across the synapse to the Postsynaptic neuron.
With all those chemicals how does a neuron determine when to fire and when to withhold firing? Some chemicals are excitatory and others are inhibitory. Additionally, different chemicals arrive at separate times, and to separate parts the the neuron. Taken together this means that neurons integrate information in
a spatially and temporally meaningful way to change behavior!
Have a look for yourself and simply Google: acetylcholine, dopamine, serotonin, glutamate, or GABA to start.
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